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Kerriamycin B inhibits protein SUMOylation
https://sucra.repo.nii.ac.jp/records/13437
https://sucra.repo.nii.ac.jp/records/13437e734aaa4-d35f-448d-952c-71c77d26e76c
名前 / ファイル | ライセンス | アクション |
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A1002894.pdf (250.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-06-18 | |||||
タイトル | ||||||
タイトル | Kerriamycin B inhibits protein SUMOylation | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | kerriamycin B | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | SUMO-1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | SUMO-activating enzyme (E1) | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Fukuda, Isao
× Fukuda, Isao× Ito, Akihiro× Uramoto, Masakazu× Saitoh, Hisato× Kawasaki, Hisashi× 長田, 裕之× 吉田, 稔 |
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著者 ローマ字 | ||||||
Fukuda, Isao | ||||||
著者 ローマ字 | ||||||
Ito, Akihiro | ||||||
著者 ローマ字 | ||||||
Uramoto, Masakazu | ||||||
著者 ローマ字 | ||||||
Saitoh, Hisato | ||||||
著者 ローマ字 | ||||||
Kawasaki, Hisashi | ||||||
著者 ローマ字 | ||||||
Osada, Hiroyuki | ||||||
著者 ローマ字 | ||||||
Yoshida, Minoru | ||||||
著者 所属 | ||||||
著者 所属 | ||||||
著者 所属 | ||||||
著者 所属 | ||||||
著者 所属 | ||||||
著者 所属 | ||||||
埼玉大学大学院理工学研究科 | ||||||
著者 所属 | ||||||
埼玉大学大学院理工学研究科 | ||||||
著者 所属(別言語) | ||||||
著者 所属(別言語) | ||||||
著者 所属(別言語) | ||||||
著者 所属(別言語) | ||||||
著者 所属(別言語) | ||||||
著者 所属(別言語) | ||||||
Graduate School of Science and Engineering, Saitama University | ||||||
著者 所属(別言語) | ||||||
Graduate School of Science and Engineering, Saitama University | ||||||
書誌情報 |
JOURNAL OF ANTIBIOTICS 巻 62, 号 4, p. 221-224, 発行日 2009 |
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年月次 | ||||||
2009-4 | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00218820 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1038/ja.2009.10 | |||||
関連サイト | ||||||
内容記述タイプ | Other | |||||
内容記述 | http://www.nature.com/ja/journal/v62/n4/abs/ja200910a.html | http://www.nature.com/ja/journal/v62/n4/abs/ja200910a.html | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Protein SUMOylation has recently been shown as one of the major post-translational modifications involved in a variety of signaling pathways in cells. In the course of our screening program using an in situ SUMOylation-detecting system, kerriamycin B, which had been originally isolated as an antibiotic, was identified as a novel inhibitor of protein SUMOylation. Kerriamycin B inhibits both in vitro and in vivo protein SUMOylation by blocking the formation of the E1-SUMO intermediate. Our findings will provide not only a novel tool for investigating the role of SUMO conjugations but also useful information for developing therapeutic drugs. | |||||
版 | ||||||
[著者版] | ||||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | text | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
作成日 | ||||||
日付 | 2009-06-18 | |||||
日付タイプ | Created | |||||
アイテムID | ||||||
A1002894 |