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実験室内分子進化過程の熱力学的および情報論的解釈
https://sucra.repo.nii.ac.jp/records/13340
https://sucra.repo.nii.ac.jp/records/133408f60332b-18e1-470a-91bc-f370b25b5b15
名前 / ファイル | ライセンス | アクション |
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A1002784.pdf (885.3 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-10-20 | |||||
タイトル | ||||||
タイトル | 実験室内分子進化過程の熱力学的および情報論的解釈 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | in vitro evolution | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fitness landscape | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | information | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | thermodynamics | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | sequence space | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
相田, 拓洋
× 相田, 拓洋× 伏見, 譲 |
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著者 ローマ字 | ||||||
Aita, Takuyo | ||||||
著者 ローマ字 | ||||||
HUSIMI, Yuzuru | ||||||
著者 所属 | ||||||
産業技術総合研究所生命情報科学研究センター(現 : 埼玉大学大学院理工学研究科) | ||||||
著者 所属 | ||||||
埼玉大学工学部機能材料工学科 | ||||||
著者 所属(別言語) | ||||||
Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Rational Evolutionary Design of Advanced Biomolecules (REDS) Group/JST, Saitama Small Enterprise Promotion Corporation SKIP City(Present : Graduate Sc | ||||||
著者 所属(別言語) | ||||||
Department of Functional Materials Science, Saitama University | ||||||
書誌情報 |
生物物理 en : Biophysics 巻 46, 号 3, p. 137-143, 発行日 2006 |
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年月次 | ||||||
2006-5 | ||||||
出版者名 | ||||||
出版者 | 日本生物物理学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05824052 | |||||
関連サイト | ||||||
内容記述タイプ | Other | |||||
内容記述 | http://ci.nii.ac.jp/naid/110004750167/ | http://ci.nii.ac.jp/naid/110004750167/ | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In vitro protein evolution is comprehended as a hill-climbing process on a fitness landscape in sequence space, just like the protein folding is comprehended as a valley-descending process on an energy landscape in comformation space. In this review, based on a mathematical model for in vitro molecular evolution, we demonstrated an analogy between evolutionary dynamics and thermodynamics and then many concepts in evolutionary dynamics became comprehensible. By introducing thermodynamics-like concepts such as “free fitness”, it is interpreted that evolution is driven in the direction in which free fitness increases. In this process, the evolving population climbs the fitness landscape by absorbing "fitness information" as the negative entropy from the surroundings as an experimental set-up. |
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注記 | ||||||
内容記述タイプ | Other | |||||
内容記述 | rights: 日本生物物理学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation: isVersionOf: http://ci.nii.ac.jp/naid/110004750167/ |
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版 | ||||||
[出版社版] | ||||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | text | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
作成日 | ||||||
日付 | 2008-10-20 | |||||
日付タイプ | Created | |||||
アイテムID | ||||||
A1002784 |