WEKO3
アイテム
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多糖の硫酸化における位置選択性と立体化学<ミニノート>
https://doi.org/10.24561/00014852
https://doi.org/10.24561/00014852a821ae23-9927-4d55-a148-0af77e7d6f8a
名前 / ファイル | ライセンス | アクション |
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KY-AN10402595-18-08.pdf (323.7 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2009-11-12 | |||||
タイトル | ||||||
タイトル | 多糖の硫酸化における位置選択性と立体化学<ミニノート> | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.24561/00014852 | |||||
ID登録タイプ | JaLC | |||||
タイトル(別言語) | ||||||
その他のタイトル | Regioselectivity and stereochemistry of the synthesized sulfated polysaccharides | |||||
著者 |
前田, 昌徹
× 前田, 昌徹 |
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著者 ローマ字 | ||||||
MAEDA, Masaakira | ||||||
著者 所属 | ||||||
埼玉大学理学部分子生物学科 | ||||||
著者 所属(別言語) | ||||||
Department of Molecular Biology, Faculty of Science, Saitama University | ||||||
書誌情報 |
CACS FORUM 巻 18, p. 33-39, 発行日 1998 |
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年月次 | ||||||
1998-12 | ||||||
出版者名 | ||||||
出版者 | 埼玉大学分析センター | |||||
概要 | ||||||
内容記述タイプ | Other | |||||
内容記述 | A novel sulfated β-1,3-xylan product was synthesized from algal cell wall microfibril homoxylan by the N,N-dimethylformamide (DMF)-SO3 complex sulfation method. Antithrombin activity appeared in this product was 6.5 times higher than that of standard heparin. From the results of 1H- and 13C-NMR spectroscopic analysis by DQF-COSY and HMQC, it was revealed that the ordered structure of β-1,3-xylan as a triple helix decayed and the resulting conformational change had been caused by the sulfation reaction. The sulfated positions on the C-4 hydroxyl groups of the xylose residues were determined from 13C-NMR chemical shifts, and it was found that regioselective sulfation had occurred predominantly with the C-4 secondary hydroxyl groups to produce mono-substituents. Another type of sulfation of β-1,4-xylan that showed no regioselectivity is considered to have been due to the different conformation of both xylan chains such as triple helix in β-1,3-xylan and the double straight chain like cellulose in β-1,4-xylan. Therefore, the different type of regioselective sulfation of β-1,3- and β-1,4-xylan was caused by the difference in steric hindrance due to these conformations. These different types of regioselective sulfation with different linkage positions are also discussed for the secondary hydoxyl groups in β-1,3- and β-1,4-glucan after chempselective sulfation of the C-6 primary hydroxyl groups. | |||||
版 | ||||||
[出版社版] | ||||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | text | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
作成日 | ||||||
日付 | 2009-11-19 | |||||
日付タイプ | Created | |||||
アイテムID | ||||||
KY-AN10402595-18-08 |