@misc{oai:sucra.repo.nii.ac.jp:00010485, author = {河合, 雄毅}, month = {}, note = {Silicones (polydimethylsiloxane) are biologically inert material and widely used in medical treatment such as catheters etc. Owing to poor tissue adhesion, the interface of the catheter with tissue tends to be a path for bacterial entry and growth. If the tissue adheres well to the catheter by surface modification, infections are suppressed. Ion irradiation is one of the most promising methods for improving the biocompatibility of polymers. Plasma-based ion implantation (PBII) will be the best of these methods for modifying curved surfaces because it attracts ions with an electrical field applied directly onto the specimen. Tube surfaces can be modified by PBII without rotating the sample by using a columnar sample holder inserted into the tubes. We irradiated silicone sheets with Ar, Xe ions to improve of their biocompatibility. The irradiation was quite effective and percentage of cell attachment was increased at lower acceleration voltages. On the other hand, it decreased at higher voltages. Then we prepared the samples pre-treated with a sand blast to increase the roughness. It moderated the damage at higher voltages and attained more than 90% of cell attachment., 指導教員: 埼玉大学大学院理工学研究科准教授 長谷川靖洋, text, application/pdf}, title = {プラズマイオン注入法による医療高分子の表面改質}, year = {2008}, yomi = {カワイ, ユウキ} }