@article{oai:sucra.repo.nii.ac.jp:00012504,
 author = {松岡, 浩司 and 照沼, 大陽},
 issue = {4},
 journal = {Carbohydrate polymers},
 month = {},
 note = {http://www.sciencedirect.com/science/journal/01448617 | http://www.sciencedirect.com/science/journal/01448617, As an artificial ligand, a glycoconjugate polymer carrying carbohydrate moiety of lactosyl ceramide or globotriaosyl ceramide (Gb3) was synthesized. Gb3 is known as the receptor of Shiga toxin-producing Escherichia coli O157: H7. The preparation of the glycoconjugate polymer initially involves the construction of the carbohydrate moiety of Gb3 derivative which has n-pentenyl group as polymerizable group. In addition, the n-pentenyl group of the Gb3 derivative was modified and different polymerizable groups such as acrylamide group were introduced at ω-position of the aglycon. Radical polymerization of the synthesized glycosyl monomers with or without acrylamide proceeded smoothly in water using ammonium persulfate and N, N, N′, N′-tetramethylethylenediamine as usual initiator system and gave water-soluble glycoconjugate polymers having various polymer compositions. These polymers have the potential to neutralize Shiga toxin by reason of cluster effect and multivalency., text, application/pdf},
 pages = {441--450},
 title = {Synthesis of glycoconjugate polymer carrying globotriaose as artificial multivalent ligand for Shiga toxin-producing Escherichia coli O157 : H7},
 volume = {57},
 year = {2004},
 yomi = {マツオカ, コウジ and テルヌマ, ダイヨウ}
}