@article{oai:sucra.repo.nii.ac.jp:00012607, author = {原, 弘志}, issue = {1}, journal = {GENES & GENETIC SYSTEMS}, month = {}, note = {The Rcs signal transduction system of Escherichia coli regulating capsularpolysaccharide synthesis (cps) genes is activated by overexpression of the djlA gene encodinga cytoplasmic membrane-anchored DnaJ-like protein. However, by monitoring the expression of a cpsB′-lac fusion in pgsA- and mdoH-null mutants in which the Rcs system isactivated, we found that the Rcs activity was further increased by deletion of djlA anddecreased by low-level extrachromosomal expression of djlA. Furthermore, deletion of djlA ina wild-type strain led to small but significant increase of the basal-level activity of the Rcssystem. These results demonstrate that DjlA functions as a negative regulator of the Rcs system unless abnormally overproduced., text, application/pdf}, pages = {51--56}, title = {DjlA negatively regulates the Rcs signal transduction system in Escherichia coli}, volume = {81}, year = {2006}, yomi = {ハラ, ヒロシ} }