@article{oai:sucra.repo.nii.ac.jp:00012608,
 author = {原, 弘志},
 issue = {2},
 journal = {JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY},
 month = {},
 note = {In the Escherichia coli pgsA null mutant, which lacks the major acidic phospholipids, theRcs phosphorelay signal transduction system is activated, causing thermosensitivegrowth. The mutant grows poorly at 37°C and lyses at 42°C. We showed that the poorgrowth at 37°C was corrected by disruption of the rcsA gene, which codes for acoregulator protein that interacts with the RcsB response regulator of the phosphorelay system. However, mutant cells still lysed when incubated at 42°C evenin the absence of RcsA. We conclude that the activated Rcs phosphorelay in the pgsAnull mutant has both RcsA-dependent and -independent growth inhibitory effects.Since the Rcs system has been shown to positively regulate the essential cell divisiongenes ftsA and ftsZ independently of RcsA, we measured cellular levels of the FtsZ protein, but found that the growth defect of the mutant at 42°C did not involve achange in the level of this protein., text, application/pdf},
 title = {RcsA-dependent and -independent growth defects caused by the activated Rcs phosphorelay system in the Escherichia coli pgsA null mutant},
 volume = {52},
 year = {2006},
 yomi = {ハラ, ヒロシ}
}