@article{oai:sucra.repo.nii.ac.jp:00013337, author = {幡野, 健 and Yamazaki, Tetsuya and Yoshino, Koji and Ohyama, Naoto and Koyama, Tetsuo and 松岡, 浩司 and 照沼, 大陽}, issue = {39}, journal = {TETRAHEDRON LETTERS}, month = {}, note = {http://www.sciencedirect.com/science/journal/00404039 | http://www.sciencedirect.com/science/journal/00404039, A novel O-protected lactose (Gal beta 1 -> 4Glc beta 1-) derivative bearing trimethoxysilyl group at the aglycon was developed as a silane coupling agent. Reaction of the coupling agent with tris(2,2'-bipyridine)ruthenium (II) dlichloride (Rubpy) doped silica particle gave a Rubpy-doped silica particle peripherally functionalized with O-protected lactose derivative. De-O-protection of the particle with aqueous ammonia provided lactose-coating Rubpy-doped silica particles, combining luminophor encapsulated in silica matrix and carbohydrate having lectin-recognition ability. Specific adhesion of fluorescein isothiocyanate-labeled peanut agglutinin (FITC-PNA) to the lactose-coating Rubpy-doped silica particles was confirmed by fluorescence microscopic analysis. (C) 2008 Elsevier Ltd. All rights reserved., text, application/pdf}, pages = {5593--5596}, title = {Synthesis and Lectin-binding Activity of Luminescent Silica Particles Peripherally Functionalized with Lactose}, volume = {49}, year = {2008}, yomi = {ハタノ, ケン and マツオカ, コウジ and テルヌマ, ダイヨウ} }