{"created":"2023-05-15T15:25:37.714336+00:00","id":13340,"links":{},"metadata":{"_buckets":{"deposit":"c5cea595-2184-4dd8-88bc-f4fda91c92a9"},"_deposit":{"created_by":3,"id":"13340","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13340"},"status":"published"},"_oai":{"id":"oai:sucra.repo.nii.ac.jp:00013340","sets":["94:426"]},"author_link":["21616","21615"],"item_119_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"143","bibliographicPageStart":"137","bibliographicVolumeNumber":"46","bibliographic_titles":[{"bibliographic_title":"生物物理"},{"bibliographic_title":"Biophysics","bibliographic_titleLang":"en"}]}]},"item_119_date_31":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-10-20","subitem_date_issued_type":"Created"}]},"item_119_description_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_description":"http://ci.nii.ac.jp/naid/110004750167/ | http://ci.nii.ac.jp/naid/110004750167/","subitem_description_type":"Other"}]},"item_119_description_19":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In vitro protein evolution is comprehended as a hill-climbing process on a fitness landscape in sequence space, just like the protein folding is comprehended as a valley-descending process on an energy landscape in comformation space. In this review, based on a mathematical model for in vitro molecular evolution, we demonstrated an analogy between evolutionary dynamics and thermodynamics and then many concepts in\nevolutionary dynamics became comprehensible. By introducing thermodynamics-like concepts such as “free fitness”, it is interpreted that evolution is driven in the direction in which free fitness increases. In this process, the evolving population climbs the fitness landscape by absorbing \"fitness information\" as the negative entropy from the surroundings as an experimental set-up.","subitem_description_type":"Abstract"}]},"item_119_description_21":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"rights: 日本生物物理学会\nrights: 本文データは学協会の許諾に基づきCiNiiから複製したものである\nrelation: isVersionOf: http://ci.nii.ac.jp/naid/110004750167/","subitem_description_type":"Other"}]},"item_119_description_29":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_119_description_30":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_119_publisher_11":{"attribute_name":"出版者名","attribute_value_mlt":[{"subitem_publisher":"日本生物物理学会"}]},"item_119_source_id_14":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05824052","subitem_source_identifier_type":"ISSN"}]},"item_119_text_27":{"attribute_name":"版","attribute_value_mlt":[{"subitem_text_value":"[出版社版]"}]},"item_119_text_3":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Aita, Takuyo"},{"subitem_text_value":"HUSIMI, Yuzuru"}]},"item_119_text_32":{"attribute_name":"アイテムID","attribute_value_mlt":[{"subitem_text_value":"A1002784"}]},"item_119_text_4":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"産業技術総合研究所生命情報科学研究センター(現 : 埼玉大学大学院理工学研究科)"},{"subitem_text_value":"埼玉大学工学部機能材料工学科"}]},"item_119_text_5":{"attribute_name":"著者 所属(別言語)","attribute_value_mlt":[{"subitem_text_value":"Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Rational Evolutionary Design of Advanced Biomolecules (REDS) Group/JST, Saitama Small Enterprise Promotion Corporation SKIP City(Present : Graduate Sc"},{"subitem_text_value":"Department of Functional Materials Science, Saitama University"}]},"item_119_text_9":{"attribute_name":"年月次","attribute_value_mlt":[{"subitem_text_value":"2006-5"}]},"item_119_version_type_28":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"相田, 拓洋"},{"creatorName":"アイタ, タクヨウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"伏見, 譲"},{"creatorName":"フシミ, ユズル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-24"}],"displaytype":"detail","filename":"A1002784.pdf","filesize":[{"value":"885.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"A1002784.pdf","url":"https://sucra.repo.nii.ac.jp/record/13340/files/A1002784.pdf"},"version_id":"10ba5cfa-3f09-4e1c-b214-7cff8563bf6b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"in vitro evolution","subitem_subject_scheme":"Other"},{"subitem_subject":"fitness landscape","subitem_subject_scheme":"Other"},{"subitem_subject":"information","subitem_subject_scheme":"Other"},{"subitem_subject":"thermodynamics","subitem_subject_scheme":"Other"},{"subitem_subject":"sequence space","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"実験室内分子進化過程の熱力学的および情報論的解釈","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"実験室内分子進化過程の熱力学的および情報論的解釈"}]},"item_type_id":"119","owner":"3","path":["426"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-10-20"},"publish_date":"2008-10-20","publish_status":"0","recid":"13340","relation_version_is_last":true,"title":["実験室内分子進化過程の熱力学的および情報論的解釈"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-16T12:37:05.709821+00:00"}