@article{oai:sucra.repo.nii.ac.jp:00014477,
 author = {平瀬, 肇 and 岩井, 陽一 and 高田, 則雄 and 篠原, 良章 and 三嶋, 恒子},
 issue = {1654},
 journal = {Philosophical Transactions of the Royal Society B},
 month = {},
 note = {20130604, The influence of astrocytes on synaptic function has been increasingly studied, owing to the discovery of both gliotransmission and morphological ensheathment of synapses. While astrocytes exhibit at best modest membrane potential fluctuations, activation of G-protein coupled receptors (GPCRs) leads to a prominent elevation of intracellular calcium which has been reported to correlate with gliotransmission. In this review, the possible role of astrocytic GPCR activation is discussed as a trigger to promote synaptic plasticity, by affecting synaptic receptors through gliotransmitters. Moreover, we suggest that volume transmission of neuromodulators could be a biological mechanism to activate astrocytic GPCRs and thereby to switch synaptic networks to the plastic mode during states of attention in cerebral cortical structures., text, application/pdf},
 pages = {[1]--7},
 title = {Volume transmission signalling via astrocytes},
 volume = {369},
 year = {2014},
 yomi = {ヒラセ, ハジメ and イワイ, ヨウイチ and タカタ, ノリオ and シノハラ, ヨシアキ and ミシマ, ツネコ}
}