@article{oai:sucra.repo.nii.ac.jp:00014506,
 author = {仲本, 準},
 journal = {CACS FORUM},
 month = {},
 note = {The photosynthetic prokaryotic cyanobacteria generally have two copies of the groEL or chaperonin gene. The groEL1 gene forms an operon with groES, whereas groEL2 is not accompanied by groES. There is evidence for some specificity of in vivo function in these two GroELs. We have shown that GroEL1 can replace GroEL functionally in Escherichia coli, while GroEL2 cannot. GroEL1 appears to be essential in cyanobacteria, while the groEL2 gene is dispensable under normal growth conditions. However, we showed that a groEL2 mutant of Thermosynechococcus elongatus is high- and low-temperature sensitive. Our comparative biochemical characterization of the two GroELs showed that the cyanobacterial GroELs are mutually distinct and different from Escherichia coli GroEL. On the basis of our results, I propose the following hypothesis. GroEL1 plays an essential housekeeping role, like Escherichia coli GroEL. On the other hand, GroEL2 plays a role under stress that cannot be substituted by GroEL1. Cyanobacteria have acquired this unique chaperonin in order to sustain photoautotrophic life under changing environmental conditions., text, application/pdf},
 pages = {33--36},
 title = {シアノバクテリアの二種類のシャペロニン（GroEL）における機能分化《マイレビュー》},
 volume = {1},
 year = {2010},
 yomi = {ナカモト, ヒトシ}
}