{"created":"2023-05-15T15:27:36.158186+00:00","id":16472,"links":{},"metadata":{"_buckets":{"deposit":"8839eebe-56fe-4ee4-9b72-3fb495380348"},"_deposit":{"created_by":3,"id":"16472","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"16472"},"status":"published"},"_oai":{"id":"oai:sucra.repo.nii.ac.jp:00016472","sets":["95:238:630"]},"author_link":["26665","16806","26664"],"item_120_alternative_title_1":{"attribute_name":"タイトル（別言語）","attribute_value_mlt":[{"subitem_alternative_title":"Mechanism of the Determination of the Caudal Otx Expression Bo"}]},"item_120_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"27","bibliographicPageStart":"22","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"埼玉大学地域オープンイノベーションセンター紀要"},{"bibliographic_title":"Report of Comprehensive Open Innovation Center, Saitama University","bibliographic_titleLang":"en"}]}]},"item_120_date_31":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-08-18","subitem_date_issued_type":"Created"}]},"item_120_description_19":{"attribute_name":"概要","attribute_value_mlt":[{"subitem_description":"To understand the mechanisms governing the establishment of the midbrain-hindbrain boundary (MHB), which organizes the formation of the midbrain and hindbrain in vertebrate embryos, the molecular aspects of the developmental process were examined in zebrafish embryos. We first examined the regulation of the MHB-specific transcription of fgf8 that is specifically expressed at the MHB, suggesting that the regulatory mechanism is conserved during vertebrate evolution. We also analyzed the in vivo activities of intramolecular deletions in Gbx2, which contributes to the MHB development together with Otx2, revealing multiple functional subregions within the Gbx2 protein. Finally, the role of the FGF-FGF receptor in brain formation was analyzed using modified forms of FGF receptors, and showed the involvement of the growth factor signal in different aspects of brain formation in early embryos.","subitem_description_type":"Other"}]},"item_120_description_29":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_120_description_30":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_120_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24561/00016466","subitem_identifier_reg_type":"JaLC"}]},"item_120_other_language_22":{"attribute_name":"その他の言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_120_publisher_11":{"attribute_name":"出版者名","attribute_value_mlt":[{"subitem_publisher":"埼玉大学総合研究機構地域オープンイノベーションセンター"}]},"item_120_source_id_14":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"18838278","subitem_source_identifier_type":"ISSN"}]},"item_120_text_27":{"attribute_name":"版","attribute_value_mlt":[{"subitem_text_value":"[出版社版]"}]},"item_120_text_3":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Yamasu, Kyo"},{"subitem_text_value":"Suda, Yoko"},{"subitem_text_value":"Aizawa,  Shinichi"}]},"item_120_text_32":{"attribute_name":"アイテムID","attribute_value_mlt":[{"subitem_text_value":"KY-18838278-10"}]},"item_120_text_4":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"埼玉大学大学院理工学研究科"},{"subitem_text_value":"理化学研究所 発生・再生科学総合研究センター"},{"subitem_text_value":"理化学研究所 発生・再生科学総合研究センター"}]},"item_120_text_5":{"attribute_name":"著者 所属(別言語)","attribute_value_mlt":[{"subitem_text_value":"Graduate School of Science and Engineering，Saitama University"},{"subitem_text_value":"Center for Developmental Biology (CDB), RIKEN"},{"subitem_text_value":"Center for Developmental Biology (CDB), RIKEN"}]},"item_120_text_9":{"attribute_name":"年月次","attribute_value_mlt":[{"subitem_text_value":"2008"}]},"item_120_version_type_28":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"弥益, 恭"},{"creatorName":"ヤマス, キョウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16806","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"dShZsmBx","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://s-read.saitama-u.ac.jp/researchers/pages/researcher/dShZsmBx"}]},{"creatorNames":[{"creatorName":"須田, 容子"}],"nameIdentifiers":[{"nameIdentifier":"26664","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"相澤, 慎一"}],"nameIdentifiers":[{"nameIdentifier":"26665","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-24"}],"displaytype":"detail","filename":"KY-18838278-10.pdf","filesize":[{"value":"2.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KY-18838278-10.pdf","url":"https://sucra.repo.nii.ac.jp/record/16472/files/KY-18838278-10.pdf"},"version_id":"b5e24dc6-d912-4cf3-b195-e4020387b0ef"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Otx後方発現境界制御の解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Otx後方発現境界制御の解析"}]},"item_type_id":"120","owner":"3","path":["630"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-08-18"},"publish_date":"2009-08-18","publish_status":"0","recid":"16472","relation_version_is_last":true,"title":["Otx後方発現境界制御の解析"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-15T18:05:40.861708+00:00"}