@article{oai:sucra.repo.nii.ac.jp:00016473, author = {田中, 秀逸 and 井上, 弘一 and 畠山, 晋}, journal = {埼玉大学地域オープンイノベーションセンター紀要, Report of Comprehensive Open Innovation Center, Saitama University}, month = {}, note = {At gene targeting in Neuroapora, the deficient strains of non-homologous end joining, a mechanism for repair of DNA double strand break, induce amazing high efficiency. We had found this technique and gotten a patent concerning it. We had already checked disrupted strains of genes encoding KU70, KU80, or LIG4 homologues, respectively. In this study, we have newly checked disrupted strains of genes encoding XRCC or XLF homologues, respectively. As these results, it was appeared that a mus-53 strain, in which LIG4 homologue was disrupted, is most effective one for gene targeting. We also start to examine characters of random insertion of DNA fragments injected into cells in Neurospora., text, application/pdf}, pages = {28--29}, title = {糸状菌における組換えに関する研究}, volume = {1}, year = {2009}, yomi = {タナカ, シュウイツ and イノウエ, ヒロカズ} }