@article{oai:sucra.repo.nii.ac.jp:00018485, author = {乙須, 拓洋}, journal = {CACS FORUM : 埼玉大学研究機構科学分析支援センター機関誌}, month = {}, note = {Biological membrane is fluidic and the fluidity of lipids and proteins on the membrane is essential for expressing various biological functions. Determination of the accurate diffusion coefficients of biomembrane constituents is thus crucial to understand the dynamical property of membranes and its relationship with the unique biological functions. To analyze the diffusion coefficient of molecules on biomembrane, novel fluorescence correlation spectroscopy, standing evanescent-wave fluorescence correlation spectroscopy (SEW-FCS), is developed. Utilization of evanescent wave is beneficial to selectively excite molecules on a supported lipid bilayer, an artificial lipid bilayer formed on the glass surface. Furthermore, fringe pattern (standing wave) illumination achieved by the interference of two evanescent waves enables us to measure the diffusion times with two different spatial resolutions. The performance of SEW-FCS is tested by measuring the diffusion coefficient of fluorescence lipids on the supported lipid bilayer., text, application/pdf}, pages = {13--16}, title = {細胞膜中分子の拡散計測法の開発《若手研究者の紹介》}, volume = {9}, year = {2018}, yomi = {オトス, タクヒロ} }